Shari Gordon

Company: AskBio

Job title: Senior Director - Immunology

Bio:

 

Seminars:

Safety Challenges Posed by Empty Capsids & the Need for Novel Immune Modulatory Strategies 4:15 pm

Evaluating AAV empty capsids and their role in inducing both antibody and T cell responses  Assess we can improve our characterization of the immune response to AAV Learn how novel immune modulatory strategies need to be tested in preclinical models and advanced to clinical studiesRead more

day: Day One

Panel Discussion: Uncovering Unknowns About the Ratio of Percentage Full Vs Percentage Empty Capsids On Safety & Efficacy of AAV Gene Therapy 3:15 pm

What is the impact of percentage full vs empty ratio on efficacy and safety? What role does this play on immunogenicity of the gene therapy? What are the acceptable limits of empty capsids in a drug product and which assays are use to measure it? Chaired by: Sam Wandsworth, Chief Scientific Officer, UltragenyxRead more

day: Day One