Ronald G. Crystal

Ronald                  G. Crystal

Company: Weill Cornell Medical College

Job title: Professor - Genetic Medicine


Panel Discussion: Understanding the Pitfalls Associated with Monkey Models 1:30 pm

• Assessing the mechanism for how monkeys manifest toxicity in response to AAV vectors • Elucidating the mechanism for how liver damage occurs in monkeys • Exploring the differences between the monkey and human cellular immune response to better inform AAV safety understandingRead more

day: Day One

Extrapolating AAV Data from Experimental Animals to Aid in Designing Human Studies 12:00 pm

• Examining the impact of animal model efficacy and toxicity data on translating AAV therapy to the clinic • Utilizing data from mice and nonhuman primates in predicting human responses to AAV therapy • Strategies to optimize insights from experimental animals to understanding AAV safety in humansRead more

day: Day One

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