Hildegund Ertl

Company: The Wistar Institute

Job title: Professor

Bio:

 

Seminars:

Adaptive Response to AAV Therapies & the Associated Safety Challenges These Pose 4:00 pm

Mitigation of AAV capsid- and insert-specific CD8+ T cell responses Mitigation of antibody responses to AAV capsid ore the insert Mitigation of AAV-specific pre-existing immunityRead more

day: Day Two

Designing an Appropriate Immunosuppressive Regimen to Minimize Impact of the Immune Response to Administered AAV Therapies 12:00 pm

This panel will be a structured conversation designed to answer key questions such as: Discuss the best methods to circumvent the activation of both innate and adaptive immune response to the protein capsid, vector genome and transgene product to ensure no SAEs to reduce risk of clinical holds Explore immunomodulating and suppressive regimens currently used…Read more

day: Day Two