Mastermind Session: Identifying Alternative Models to Reduce the Need for Animal Models & Exploring the Challenges Associated with Providing Accurate Safety Signal Information

Time: 4:30 pm
day: Day One


This mastermind will give each group the same set of questions surrounding this idea, and then answers will be collated at the end of the session and distributed to all attendees post-conference to gain insights into current perspectives in the field, and suggestions and ideas of relevant actions we can take as a collective to navigate misconceptions in gene therapy

• Exploring the viability of organoid chip technology to help aid in AAV safety signals 

• Delving into the challenges of utilizing 3D organ models to better define the AAV safety profile in the liver

• Discovering other in vitro models available and assessing how well they can inform AAV safety in comparison to animal models