Dorsal Root Ganglia findings in Nonhuman primates – Lessons learned with Onasemnogene abeparvovec-xioi (Zolgensma)

Time: 2:00 pm
day: Day Two

Details:

  • DRG microscopic findings have only rarely had clinical (inlife) correlates in NHP
  • DRG microscopic finding severity appears related to high transgene
    transduction and/or expression
  • No signal detected in treated patients to suggest sensory changes or
    abnormalities

Speakers: