Dorsal Root Ganglia findings in Nonhuman primates – Lessons learned with Onasemnogene abeparvovec-xioi (Zolgensma)
Time: 2:00 pm
day: Day Two
Details:
- DRG microscopic findings have only rarely had clinical (inlife) correlates in NHP
- DRG microscopic finding severity appears related to high transgene
transduction and/or expression - No signal detected in treated patients to suggest sensory changes or
abnormalities