Characterizing the Potential Risk of Integration with AAV Vectors & Discovering How to Test & Show an Integration Profile in Humans
Time: 4:00 pm
day: Day Two
Details:
• Exploring how targeted and non-targeted deep sequencing methods can be leveraged to characterize integration profiles in human patients
• Comparing human with NHP hepatocytes to better understand value of measuring integration in pre-clinical models
• Identifying molecular and genomic tests available to assess causality of cancers in patients treated with gene therapy